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Key takeaways: GLP-1s slow gastric emptying, which can reduce how well oral contraceptives are absorbed Weight loss on GLP-1 therapy may lower blood pressure enough to require adjusting your current medications Thyroid medications like Levothyroxine may become too potent as your body mass decreases on GLP-1 therapy Regular monitoring with your clinician keeps all your medications properly aligned as your body changes Key Issues to Consider with GLP-1 Medications GLP-1 medications work by slowing down the gastric emptying process, meaning it takes longer for food, and oral medications like contraceptives, to be absorbed into the bloodstream